[/]: If nicotine like like the brain receptors that love muscle receptors, so just one cigarette can get you killed. Today, scientists have finally understood why this molecule has been so critical — this discovery to solve the problem of smoking addiction has brought the dawn.
Nicotine (or any kind of molecule) If you want to and its receptor interaction, both of these substances must be separated to form a chemical bond, that is, the elements to carry the opposite charge, while also having the receptor binding sites, and thus the final formation of a "skeleton". Although nicotine in the brain and muscles in the receptor is almost the same, but why only brain receptor like nicotine, while muscle receptors but fear that refuge not?
After ten years of research work, the United States, California Institute of chemists Dennis Dougherty and his colleagues have finally found the answer to the question — all differences are a simple amino acid. In the vicinity of the "skeleton", the brain receptor molecules with a lysine, and muscle receptor has a glycine. Then the lysine molecules produced exactly what role? researchers found that it changes the brain receptors "skeleton" shape so that its negative charge to more effectively and close to the nicotine molecules, a process that is what people call cation — send interaction.
For muscle receptor "skeleton", it can perfectly into known acetylcholine molecules. When the research team will Dougherty muscle receptors of glycine replaced by lysine, muscle receptor can like acetylcholine "hug" nicotine. But fortunately it didn't really occur in the human body, because smoking can quickly cause abnormal contraction resulting paralysis of muscles, which makes some people feel shortness of breath.
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