Interview: uncovering the mysteries of stem cell update

[/]: A cardiac physicians from China to the United States by shanghairuijinyiyuan Kansas City, virtuous (Stowers) medicine began on the in-depth study of stem cells. He is Xie Yu, he and his wife-Indian cooperation with Tong, a new method on mouse bone marrow hematopoietic stem cell behavior for real-time tracking, discovery of the talus bone marrow cavity surface 16 micron range is a blood stem cell like micro-environment. January 1, published in the journal nature published the results. Xie Yu and Yan Tong for article authors of tied for first place. The beijingkejibao law: you are the heart of a physician, why focus on stem cells? Xie Yu: about 5 years ago, I met such a clinical cases: a United States friends to visit China, sudden large areas of acute myocardial infarction, into shanghairuijinyiyuan. We use the best drugs, emergency treatment. Patients with symptoms once get better, but because of the large area of myocardial necrosis, his heart failure symptoms gradually increased, we still couldn't save his life. The root cause is necrosis of myocardial cannot be regenerated, only a lot of scar in place, the heart of the "blood pump" lost power. Currently, feasible method is cardiac transplantation, but the source of the heart. If you have a suitable stem cell transplantation in and proliferation, it is possible to use the new cells instead of dead cells, and fundamentally solve the problem. The beijingkejibao ": this outcome, can resolve stem cells application? Xie Yu: this is a very basic research, although not directly address the issue of the application, but, through it, we know the transplantation of hematopoietic stem cells where the proliferation of proliferation and why. Through observation of a single stem cells in vivo dynamic behavior, can help people better understand the characteristics of stem cells, to more effective application of stem cell Foundation. Today, the stem cells to cancer, coronary heart disease, diabetes, and other treatment research has also been expanded, a better understanding of the characteristics of stem cells, you can make it more effective proliferation, and used more and more extensive treatment in the field. The beijingkejibao ": you and your wife and to do research, ever academic divisions? Xie Yu: often have. For example, stem cells like micro-environment, Indian Tong believes stem cells in different States will like different micro-environment, still likes osteoblasts in when the micro-environment, active like vascular microenvironment. I think the stem cells are usually located in the osteoblastic cells microenvironment, vascular only stem cells leads to systemic circulation of a channel. Experiment of confirms that we are right. Stem cells microenvironment including osteoblasts and blood vessels, they are inseparable. There are differences, we speak with data. The United States Beijingkejibao ": in the two years that you feel is the greatest? Xie Yu: domestic scientific research development, equipment and laboratory conditions are close to the United States. A lunch, I chat with colleagues from the United States, referring to the national laboratory of conditions and the size of shanghairuijinyiyuan they were all very surprised. I think that there is a gap between China and the United States is in fact research support system. At Stowers, if you initially do not use the instrument, do not do animal experiments will have specialized training to you until qualified.