According to foreign media reports, in a new high power microscope, scientists to Germany for the first time on a single-cell growth but to vertebrate embryos observation, the embryo has a heartbeat. The study process, development of small fish are three-dimensional digital reconstruction, this may help scientists uncover how human organ formation in secret, and learn more about some of the genetic basis of disease.
This study is located in Germany Heidelberg's European Molecular Biology Laboratory, research leader Joe Hachem · Wittbrodt (Joachim Wittbrodt) said: "This gives us the ability to animal life formation process of observation. In observation of the process, you will find many cells develop into the embryo with heartbeat. "Research papers published in science magazine.
Wittbrodt, prior to this, the scientists have on Macroinvertebrates made similar observations, for example, only have a few hundred cells of earthworms embryos, but until now they had copied vertebrates are in the same observation, vertebrate embryos by tens of thousands of cells. He said that the adoption of a sufficient to tens of thousands of cells at the same time to trace and does not undermine or even destroy embryos of high power microscope, Germany Research Group eventually overcome this obstacle.
With the help of this high-energy telescope, they use a lot of direction different light on the embryo is scanned, do allow the computer to create three-dimensional images related to provide full details of the development process. Currently working in Germany Heidelberg University Wittbrodt says: "the microscope's energy is controlled in the proper range, at the same time, the resolution of the embryo is also very soft and very fast, because you need to move things to observe. This is like a huge jigsaw puzzle, we can see each piece, and thus get the entire puzzle. ”
Research used in zebrafish embryos from, also known as Zebra Chub, have always been the darling of researchers because they cost less than the rat for cultivation, and have many and human similar biological characteristics. In order to develop into a complex organism, embryonic cells must split, split the cell in the body after the tour, the formation of complex shapes and specific organizations. Researchers said they now to learn more about the cells move process, and before you think there are some differences.
High power microscope, it can also be used for observation of the rat, chicken and frog species. Wittbrodt, similar experiments will ultimately help scientists better understand how the spread of cancer, or arthritis in patients like this autoimmune disease, why cells sometimes and body to do. "This kind of experiment for people with a lot of sense, our experiment is just a start. ”
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