[/]: 23 November, 11-year-old Yu Yi Xuan in Concord for surgical extraction of stem cells, these precious "seed" transplanted into their mothers living with leukemia. Recently, this strong young became media hot spots, he took the initiative of the recipient to save the mother's story touched many people.
They are lucky. It is reported that children and parents the chance of a successful bone marrow matching almost equivalent to the lottery, not to mention the people who know each other, so both in films and TV programs or in real life, there are so many people struggling waiting for proper bone marrow.
"If the baby placenta stem cells save up, later encounter similar disease cure hope. "" Human placental stem cell Bank, "said the Chief expert yukui. Just like banks, deposit, usually when they are needed.
Stem cells: cells
Stem cells have extraordinary regeneration capacity, can generate a variety of specific differentiation of functions of cells and tissues and organs, this is its two fundamental characteristics.
Extraordinary regeneration capacity so that the stem cells can be split into a large number of cells that meet medical needs, because using stem cells to treat a disease, usually takes up to millions of cells.
The differentiation of the generated function cell can play an important role in the treatment of specific diseases. Yukui said that can differentiate into red blood cells carry oxygen, differentiation into islet cells produce insulin, etc. Because of this characteristic, stem cells are referred to as the "universal cell", a biomedical research.
Stem cells are a few different sources. The first source is the early embryo, that embryonic stem cells, it is in early human embryo — blastocysts (fertilization after about 5-7 days) of undifferentiated cells. Secondly, the stem cells derived from adult individual organizations, such as bone marrow, blood, fat, etc., but this little number of stem cells. In addition, the stem cells can also come from baby placenta and umbilical cord blood.
Due to its characteristics, stem cells become overcome many of the regeneration of one of the important direction. "Some diseases cannot be used with drug therapy, such as the spine broke its own grows again, another example of senile dementia patients is brain cell function degradation, drugs are also resumes, while these functions are possible through stem cells generate specific functional cells to recover. "Yukui said.
Unsafe animal serum
According to reports, placental stem cell differentiation is less profitable than embryonic stem cells is slightly lower, but not the ethics of embryonic stem cells; compared with umbilical cord blood stem cells, a placenta weighing about 700-800 grams, umbilical cord blood is only 80-90 grams, the number of placental stem cells more; and bone marrow stem cells, placental stem cell differentiation of better, and do not need to invade the bone marrow samples.
According to the international yukui describes many stem cell Bank, the majority of these stem cell Bank has a cord blood bank. The start is the cord blood collected direct freezing, and then start the umbilical cord blood in nucleated cells isolated from culture, built in umbilical cord blood cells library. And until recent years, from the umbilical cord blood cells in further isolate the stem cells.
But so far, almost all of the stem cell Bank are private, not public, that is, his own cord blood stem cells saved only by his own use. Since the second half of last year, some of the largest umbilical cord blood stem cell Bank also proposes to establish a placental stem cell Bank, but is still not suitable for clinical application.
So, what kind of stem cell bank meets the clinical application of criteria? yukui said, clinical application of the standards are more complex, such as stem cell culture process of stem cells to keep non-activated charging body, cell groups, to pure, etc, but the most basic, no cell is saved to the animal source of exposure.
At present, domestic and foreign many studies have used animal serum to culture cells, this is a likely source of imported animal virus material, but the current technology does not detect its potential danger. "We chose human umbilical cord blood substitute animal serum, and joining the different growth factors that ultimately proved very optimistic. "Yukui said.
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