Harvard scientists for the first time in mice produce human vascular

Keywords: mouse in vivo human vascular

[] Hearing: åœ — äº¬æ — July 21, message, according to the United Kingdom Broadcasting Corporation reported that United States the cycling magazine reported that Harvard scientists have successfully use human cells in mice produce new blood vessels, which historically was the first time. They said that this will ultimately bring Gospel heart patients.

In the development process, from the blood and bone marrow extracted progenitor cells formation vascular cell lining and lining around. A United Kingdom experts say, Harvard University's research has great development prospects, will ultimately allow laboratory of organ transplant becomes a possibility.

Scientists would like to see is the new rapid nurturing a capillary network of competence. Training vessels in medicine has many potential applications, especially in the treatment and destruction of tissue blood supply-related diseases, such as a heart attack after myocardial blood flow. However, these vessels of the complex structure of slowing blood supply process.

In this study published in the circulation of the latest research, scientists use two progenitor cells — have similar ability of stem cells – formation of different types of cells. Endothelial progenitor cells have the capacity to form the vessel lining, mesenchymal progenitor cells lining the formation to the supporting role of nearby cells. And a large number of extraction from embryonic stem cell therapy of traditions differ, progenitor cells from adult bone marrow or umbilical cord blood,. In the laboratory and the promotion of growth in chemical substances in the mixture, the progenitor cells are implanted into mice, during this period, the scientists of the immune system of weakening the mouse in order to avoid rejection.

7 days, mice a "strong" of new vascular network, and the mouse itself together and start shipping vessels. Leading the study of Joyce · Bischof (Joyce Bischoff), said: "the true meaning of the study is that we use is from the blood or bone marrow cells obtained instead of extraction or use full maturity of the blood vessels. "Liverpool United Kingdom organization Engineering Center Nick · Rhodes (Nick Rhodes), said:" the result is very interesting, but also very promising. Artificial vascular will eventually connected with the other organs, blood supply to the body. Although this tool is not yet applied to clinical, but it is worth noting that their experimental verification of a small amount of blood can be used to cultivate a healthy capillary network. ”