X-ray virus DNA Nano-University of California
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By using powerful x-ray concentrated rays a herpes virus, no staining, United States University of California at Los Angeles, scientists took the virus first high-definition images. This technology is the so-called x-ray microscope, can promote the development of the treatment of different diseases of new drugs. A similar technique is x-ray crystal method, [] newsletter: this technology has been applied for many years, for the determination of many important protein structure, including the DNA's double helix. Responsible for the study of United States University of California at Los Angeles, John m Europe said: "this is a very important technique that many Nobel prizes are so technical. ”
X-ray crystallography of deficiencies is only applied to the Crystal, DNA and some protein after enough repetition can a Crystal, but other proteins, particularly found in the cell membrane protein cannot form a Crystal, as they will not enough soft and changeable, of course, the entire cell or Crystal. M Europe said: "like human cells, there is no second person's cells are strictly identical. "[The] hearing: m euro and his colleagues through the use of the world's most powerful x-ray machine broke this limitation. This x-ray machine in Japan in the SPring-8 synchrotron.
Scientists chose herpes viruses because of its relative diameter 100 – 200 nm, and it also have significant medical value. Its operation is: they will this virus into the synchrotron, after x-ray alignment this samples for irradiation. But on the other side of the camera can detect another release of light changes slightly, and then by computer software to x-ray pictures taken together with that form the overall image of herpes virus. M-European Group that created the first non-staining of a single virus image, appeared []: this than other techniques for image small three orders of magnitude. Other cells and viruses of image is obtained through dyeing and slices, then the picture together with, the formation of the whole image, but this procedure seriously undermining important life information.
New technology can take a 22 nm big things, but scientists said Stanford University are developing more powerful x-ray machines, can take a smaller proteins and cells of the clarity of the image. These images will be the drug discovery and development of the Gospel [] hearing: m euro. "From a protein's structure can learn about its features, then we develop a new drug can make this protein lost its function. ”
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