Cancer cell proliferation mystery mutiny with normal cells

Technology channels () message: electric on cancer patients, cancer cells began to spread in the whole body (i.e., transfer) at the moment is the fear of disease. Recently, scientists on the mystery general process gives a new interpretation.

Scientists pointed out that cancer cells in the metastatic process will encounter many difficulties, the first thing to go through dozens of variations, and to overcome the effects from the cell adhesion and change shape through the dense connective tissue. After a successful escape, cancer cells into the blood through the blood vessels, where it also attacks may be attacked by the white blood cells.

Next cancer cells through the blood vessels entering a new organ (now known as the "micro-transfer"). Here, the cancer face and unfriendly environment (referred to as "micro-environment"), some cells immediately killed, some died after splitting a few times, there are some remains of hibernation, the survival rate of only one of hundreds of millions of minutes.

Surviving cancer cells to regenerate and colonization, become a laboratory can be found in the "transfer" visible to the naked eye. With the transfer of development, it pushes away the normal cells, damaging organ function, last fatal.

So why cancer cells to specific organs transfer? for example, breast cancer will be transferred to the brain, liver, bone and lung, prostate cancer often shift to the bone, and colorectal cancer are often transferred to the liver. Scientists pointed out that this is because the target organ of some cells "mutiny", as the cancer cell proliferation has created a favourable "micro-environment", which involves both normal cells within the Organization, also involved in the immune cells in vivo patrols.

For example, there is evidence that macrophages in the white blood cells may help cancer cell colonization. People once believed that in the event of a transfer of cancer cells can find a large number of macrophages, because macrophages in the battle with cancer. But now it is thought that these macrophages in some way helped the spread of cancer cells. It is believed that there are some normal cells to generate the target organ of cell structure become loose enzymes, as cancer cells spread to create space.

Some researchers at the "micro-environment" theory to the next step and look what differences in the genetic composition of some cancer patients more prone to cancer metastasis. This study may eventually lead to a simple blood test, this test can predict who is more likely to occur Cancer Metastasis, and ultimately provide customized treatment plan. Transfer risk more people will get more active treatment, not too likely transfer of people you can avoid unnecessary, bad treatment.