In H5N1 highly pathogenic avian influenza outbreak threat to human health by pressing situations, including my own, more countries are Ratkah people with bird flu vaccine development work.
However, the United States in the area of influenza virus top scientists released a new study has sounded a warning to the people: avian influenza viruses with regional characteristics of the "branch", this means that countries only under a virus "branch" developed by the human vaccine is likely to be invalid. Development of human vaccine
Shall take into account the diversity of viruses
China Shantou University School of medicine, the Center for influenza, tube Yi Chen, Professor and United States, Tennessee, Memphis, St. Judas children research hospital, Professor of Virology · Robert Webster et al. 's study results, published in the latest edition of the authoritative and comprehensive scientific journals in the United States National Academy of Sciences.
Scientists from China, Hong Kong and the Mainland of poultry and migratory birds of 1 000 secretions, extracts the H5N1 avian influenza virus samples, and other parts of Southeast Asia and other virus samples for DNA comparisons. They found that the virus originated in 1996 in China's Guangdong's original H5N1 virus, but now in different parts of the bird's virus gene mutation has occurred, the differentiation into a region of "branch". For example, the popular over the years, the past 10 years has been in Viet Nam there have been three cross variation.
Research Group in the report suggest that the avian influenza virus will soon appear in multiple "branches" of reality shows, to prevent avian influenza outbreak, the virus only on a "branch" to develop human vaccine is "quite adventurous", must take account of the diversity of the virus. "South-East Asia and China in the South of the avian influenza virus Antigen regional differentiation, development of current human vaccine efficacy of presented enormous challenges. "In addition, they also pointed to the need to follow the virus mutation and quickly update the vaccine, which prevent avian influenza outbreaks is important.
Against the influenza virus vaccine States researched
Global infectious diseases and public health experts are most worried about is that highly pathogenic avian influenza viruses once you break the population immunity defense, evolution is easily in the crowd spread of influenza virus that will cause a lot of infection and can cause millions of deaths. Effective vaccination is the rapid establishment of human immunization barriers blocking the spread of influenza pandemic to reduce and reduce their risk of effective means. To this end, the world's scientific personnel as well as the fight against the "bird" made unremitting efforts. In people with bird flu vaccine research and development area, China has reached the world-class level. Last November, the first in the world developed SARS vaccine Beijing kexing biological products co., Ltd. and the Chinese Centre for disease prevention and control research and development of joint responsibility for China's "bird flu vaccine for human use" project by Ministry of science and technology project acceptance. The project is currently in phase I clinical trials phase, phase II clinical trial in the absence of special circumstances, will be left in June of this year. If you encounter an emergency situation, the approval by the relevant State departments, human vaccine can immediately put into production. In addition, according to my flu and SARS virus experts, Wuhan Institute of Virology, Chinese Academy of Sciences, Professor Chen, including the Shanghai Institute of biological products, a number of research institutions in both human vaccine research and development.
Occlusion culling poultry or the source of transmission is most effective
Sino-US joint research team found that the different "branch" of gene analysis shows that the virus is mainly spread virus poultry and poultry products in local transport and trade, viruses are migratory birds migrate then played a secondary role. They speculate that the avian influenza in poultry in the outbreak, the virus from infected poultry to migratory birds, and raises the outbreak in migratory birds. Part of the migratory birds could survive in the outbreak, who have viruses, they hatchling in winter, and other movements in the virus to a distant region of poultry.
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