Japan researchers for the first time in the world by human stem cells implantation in rat embryos and nurture human kidney tissue, this outcome is expected to help solve the kidney transplantation.
According to Japan's daily news 10/reports, Japan Tokyo Chee Wai will Medical University and the Autonomous University of researchers from human bone broth stem cell, set its implantation in 11 days half rat embryo may take out of the kidney. At this point, the rat embryo viscus has not yet formed, immune function is not started, foreign organisations of rejection is weak, to facilitate the rapid human stem cell division and growth.
The researchers found that the embryo was implanted in rats, two days after human stem cells to differentiate into bear the main function of the kidney wire ball and urine thin tube. Researchers confirm that these have kidney tissue from the blood into urine.
They put the generated wire ball and urine thin tube portable to other rat peritoneal covering the abdominal organs in greater omentum, results of new blood vessels start moving in the direction of silk sphere. Implantation of organization eventually develop into only one-tenth ordinary rat kidney size of human kidney tissue.
Researchers believe that this technology is mature, can be severe renal failure in patients with bone marrow stem cells implantation in pigs, and other physical larger animal embryos in stem cell differentiation into kidney patients with reimplantation after. And so the vessel within the omentum extends to transplant organizations, these organizations will be able to filter urine. In this way, patients do not need artificial dialysis or having to wait for a kidney donor.
The researchers also noted that the transplant organization how to avoid the heterologous virus infection in animals is subject to be solved in the future.
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