Technology channels () message: smoking causes blindness is not sensational. Recently, this reporter has learned from the Shanghai Institute for Nutritional Sciences College of life sciences, the Institute for health research group and Liu United States scientists cooperation to a new study shows that smoking is a major component of smog — Acrolein, is the eye health "chronic killers", thus from molecular cell level reveals the smoking cause age-related macular degeneration of the retina.
According to a survey conducted by the United Nations, and every year about 20 million worldwide — 25 million people suffer from age-related macular retinal
Diseases, of which approximately 50% of the patients eventually blindness. Epidemiological studies that smoking, antioxidant food intake too little could be an important cause of illness, but its etiology remains a mystery.
According to the project researchers Liu Bo and Sun-Juan, Acrolein toxicity than "blood killer" formaldehyde worse. It attacks cells talk strategy: from the cell's "energy factory" — mitochondrial underarm, cut off the cell energy supply. Once the energy supply reduction, the organization functional cells began to decline, lesions that follow. Acrolein "talons" to the eye, causing the leading photographic retinal pigment epithelial cells from oxidative damage, resulting in a decline of mitochondrial function, thereby affecting the eye the metabolism of the individual organizations, and gradually caused the senile macular retinal lesions that might eventually lead to blindness.
Researchers find a series of nutritional substances that can act as an "umbrella" of mitochondria. If a certain concentration of mitochondrial nutrients α-lipoic acid, retinal pigment epithelial cells play a protective role. However, said Liu Bo in the prevention of senile macular retinal best method or reject smoking and avoid second-hand smoke. Of course, the clinic by using a certain dose of mitochondrial nutrients as drug-assisted constituents, is expected to become the preventive treatment of the chronic diseases, the prevention of blindness.
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