Scientists find influenza virus control human cells (figure)

　　

Information: avian influenza virus photos

[/]: According to foreign media reports, European scientists discovered influenza virus control human cells and human cells for their self replicating machines. The study published in the United Kingdom in the journal nature.

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Researchers said they found the culprit, it is a viral enzyme, may now it has become the target of pharmaceutical experts specialize in. This virus activity near the polymerase, PCR will control its organs to synthetic virus proteins. To do this, you must remove cell DNA polymerase molecules called "hat" (cap) gene label. Hat do a similar "authorized keys" of the protein synthesis, is responsible for starting the machine, and then is added to the polymerase. "Grab Cap" is called PA polymerase subunit

Participation in the research labs of France Grenoble city European Molecular Biology Laboratory of Stephen · Kusak said: "on the influenza virus control human cells new understanding that PA has become a promising antiviral targets. Suppression of split is the cap to prevent flu effective method, because influenza viruses cannot proceed further propagation. Now, we know that the development of new medicine that focuses on what areas. ”

According to who, each year the outbreak of the flu that 300 million to 500 million people suffer from a serious illness, 25 000 to 50 000 people die. Flu outbreak is the influenza virus gene seasonal changes of a minor. However, even more worrying is the virus form new genes that make up as no one is immune to pathogens. This is the 1918 to 1919 eruption resulted in tens of thousands of people die of so-called "influenza" in Spain. It also raises awareness about avian influenza H5N1 panic, the H5N1 virus is from poultry to humans of the new variety, but also prone to human transmission. Health officials to promote the development of new drugs to tackle this threat, because the current antiviral therapy only 5 species.

The study group last year found the polymerase, another important part is called the subunit PB2, it recognizes the "caps", and then bind it. After the cap will die off. European Molecular Biology Laboratory issued a statement saying: "together, these two discovery provides a nearly perfect influenza virus control human cell of the screen grab CAP mechanisms. ”