[/]: North America a young scientist Ethan Clark Garner as he related bacteria actin cytoskeleton-like protein and DNA isolation, Assembly and regulation of, was nominated for GE & science young life scientists award winners. This includes the 2 million 5 thousands of awards competition is made by GE Healthcare companies and Science magazine joint financing.
Garner on December 11, at the award ceremony in Stockholm, Sweden on molecular biology research areas of the prize. He won the award of the title is "the smallest known DNA separation machinery — reconstruction of plasmid spindle and dynamic analysis," the paper was in December 5, Science magazine.
Science magazine's Executive Editor Monica Bradford said: "this award is granted to the world within the field of molecular biology of outstanding doctoral research. On promising young molecular biologists career early support on scientific progress is important. ”
Ethan Garner's award-winning thesis describes a simple system to help ensure that a split of the bacterial cell, copy it to the split of genetic material. His research will focus on the R1 plasmid, gaizhi particles are found in e. coli DNA rings that produce the bacterial resistance to antibiotics plays a key role. ParR and ParM these two protein plus gaizhi tablets of a section on DNA sequence parC, forming a spindle, the spindle is copied into the plasmid R1 cell opposite ends.
Garner said: "our research shows that in a test tube, only three from plasmid DNA separation of gene can, through the study the organelles that we can process on the basis of an analysis of the mechanism. "Garner in an interview said:" the remarkable achievements, biology has a way with minimum method to solve seemingly complex DNA isolation. ”
Through reconstruction in the test tube, the system shows Garner ParR and ParM is how to form a compound can be stable ParM, which can then be assembled to be composed of spindle of filament-like body. ParM only in its both ends with the parC/ParR complex before forming stability of silk. Garner said that his Institute for basic biology of an important issue, namely, the basic principles of cell division. His discovery but also for the development of a new ParM as target offers the possibility of antibiotics.
GE Healthcare's President and CEO Peter Ehrenheim said: "over the years, I applied for GE and Science Awards of high quality papers. This year's winners are very good young scientists. ”
Ethan Garner was born in Richland, Washington. Washington State University, he obtained a Bachelor's degree in biochemistry. He is the University work together with Keith Dunker, protein disorder region within the forecast tool. He studied at the University of California at San Francisco campus, Dyche Mullins in prokaryotic polymer dynamics and regulating postgraduate work in the field. Garner in Boston and Tim Mitchinson, xiaowei Zhuang and Alice Ting together in the interpretation of the prokaryotic DNA isolation procedure.
Since 1995, GE & Science Prize for young life scientists found those in the early stages of their career which has become famous young molecular biologists. To date, approximately 58-area winners and 14-bit winners won this award.
From Washington University Tanxu is North America Award, is because the plant growth hormone auxin features research and awards. He explained: "this work is involved for as long as a century of Botany, namely simple plant growth hormone auxin is how to plant life so many aspects of the impact. It is very gratifying, we find the same auxin works can be implemented in the process of drug discovery, helping people design for the treatment of cancer and other diseases. ”
He went on to say: "I get GE & Science Award and feel extremely honored. I thank the GE and science for their generous support. I would especially like to thank my doctoral thesis supervisor Dr. Zheng Ning for my firm support and encourage, these will continue to be my scientific career of the beacon. ”
The GE & Science Award applicants are in 2007 Ph.D. degree, doctoral thesis submitted to them under a thousand word essay. On their passage of the judgment is based on the quality of its research, as well as the applicant clearly explain their research is how to make contributions in the field of molecular biology. Their research is involved in the physical and chemical properties of biological molecules.
A panel of judges selected GE & Science Award winners, and will be in four areas (i.e., North America, Europe, Japan and all other countries) presented the regional awards. Regional winner of the prize money to $ 5000.
In addition to the award, the 2008 regional winners are:
Tanxu (North America): his essay entitled "Plant Hormone Auxin Functions as Novel Molecular Glue". Tanxu before the age of 18 is spent in Changsha, China. His high school crush on the biological
And obtained a biology Olympiad competition. He's in Hefei University of science and technology to obtain a Bachelor's degree (B.S), then came to Seattle Washington University graduate school. The principal under the guidance of Zheng Ning, tanxu select ubiquitin protein ligase of structural biology as his research papers. In order to expand the scope of his research at the Harvard Medical School Tanxu started by Steve Elledge men engaged in post-doctoral research.Sabrina Büttner (Europe): she's essay titled "Endonuclease G Regulates Cellular Fate." Büttner was born in Germany in Mutlangen. She's in Germany Eberhardt-Karls University research biochemistry, and in 2004 received an honorary degree. University of Graz in Austria, under the direction of Frank Madeo, her dissertation research on aging and oxidative stress, yeast programmed cell death, namely in S. Cerevisiae search for molecular mechanisms of apoptosis.
Kaori Yamada (Japan): her essay entitled "Moving PIP3 Regulates Cell Polarity". Yamada growth in Japan town Kinokawa. She obtained a Bachelor's degree from the University of Tokyo. On life science's strong interest in making her stay in the lab Yasuhisa Fukui become a graduate. In her Ph.D. thesis research, she Athar H. Chishti of lab work, the latter is she in the University of Illinois Chicago's collaborators. Yamada where driven protein (kinesin) is how neurons in transport lipid Messenger PIP3 explains. Her in January 2007 completed a doctoral thesis research. She is now at the University of Illinois Chicago as postdoctoral researchers.
Sarel Fleishman (all other countries): his essay entitled "Modeling at the Gates of the Cell". Fleishman get Israel Tel-Aviv University Biochemistry degree and doctoral degree. His research in the Nir Ben-Tal Group engaged in the research. In his graduate work, he is engaged in and hereditary hearing loss and neurodegenerative diseases, cancer and bacterial resistance of the membrane protein structure, function and evolution of research. He is currently the University of Washington, David Baker laboratory for a bit of postdoctoral research personnel, is engaged in the pathogenicity of the molecules of protein-based calculation of inhibitors of design work.
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