Wuhan University researchers found that SARS coronavirus fatal point

Keywords: Wuhan University SARS coronavirus fatal point SARS

[]: After nearly six years, Wuhan University researchers recently discovered the deadly SARS coronavirus, is a group called "non-structural protein gene encoding nsp14". Researchers said that through this important discovery can be filtered against the SARS virus drug Foundation, and thus developed into small molecule drugs.

The reporter learned from Wuhan University, found that the genes encoding is the school of life sciences, State Key Laboratory of Virology silver Professor and doctor Dr que Tak Chen, joint authors also includes the Institute of the Chinese Academy of Sciences, Director of the center of the modern viruses and so on., Tin-wave The study results recently in international authoritative and comprehensive academic journals in the United States National Academy of Sciences College newspaper published.

2003 SARS outbreak, the medical profession confirmed SARS causative coronavirus, but the virus is how to survive and multiply, but never figure out. While this issue is crucial to prevent SARS disease. In recent years, domestic and foreign laboratories on SARS virus carried out considerable research, but for the occurrence of the SARS virus and pathogenesis is still poorly understood.

Experts believe that SARS virus though has been under control, but the natural wildlife groups still exist in SARS-coronavirus, the SARS virus outbreak of dangerous again still exists.

According to reports, the SARS virus is now the biggest discovery of RNA (RNA) viruses, RNA gene by life. Wuhan University Sciences Research Group select coronavirus RNA specific to multiple processing enzymes as the main research objective, by yeast system filters and in vitro biochemical analysis, found that the SARS virus genome 1b region encoding of a "non-structural protein nsp14" also has two RNA processing enzyme activity, and use the SARS virus replication subsystem to prove these enzymes is SARS virus genome replication required.

Participation in the research of the research staff of Chen explains, "non-structural protein nsp14" virus genetic information "disguised as" let immune system recognition not out, before you know it will be a large number of virus into a place where you want to attack, and passed for virus protection. In addition, it is also the sick protein gene into a virus, not the core of this set of encoding, and then multiple genes are not viruses. Professor Dr que Tak silver that is available through this system, find out some on SARS virus which is harmful, but harmless substances, thereby developing into small molecule drugs.

It is understood that, in 2001, the academician of Wuhan Tian wave forward-looking vision put emphasis on the new episode, sudden major viral disease research at the school of Health Sciences, established centres of modern viruses and Wuhan University at the National University's unique three-biosafety laboratories, the research school in SARS virus has a unique condition.