Tuesday, December 21, 2010

World's first cloned dog was born the "skin" RA

[] Message: according to the associated press reported that Korea Korea, Seoul National University College of veterinary medicine and Lee Hwang Woo-Suk's handle thousands of Professor August 3, ABC announced that Korea scientists announced the successful inoculation global first cloned dog, sex in public, about three and a half, the dog father is a 3-year-old Afghanistan Hound, replication technology and the world is the same as a clone sheep Dolly.

The cloned dog at April 24, was born, it has been after the birth of the "Tibetan" scientists "Palace," careful feeding, until now out with it. Scientists will it named "RA skin (Snuppy)", "Seoul National University puppy" (SeoulNationalUniversityPuppy) initials, RA leather coat color is black, white and Brown, gene testing proves that it and the dog father's genes are identical. RA skin cell nucleus from an Afghanistan hound ears skin cells and brooded over dog MOM is a Labrador Retriever.

Professor Hwang Woo-Suk 's, said: "to carry out genetic tests RA skin revealed that the genetic traits and provide exactly the somatic in Afghanistan hounds. Believes that the outcome of the clone would not only help save endangered animals, can also be used for treatment of the embryonic stem cell research. ”

The dog is the most difficult to replicate in animals

Dogs are animals in the most difficult to copy, because like other mammals, ciquan in immature ovum when ovulation, the egg in the fallopian tube 2 to 3 days slowly matured. Their initial attempt to collect eggs during ovulation, and then in the test tube to nurture and mature, but failed. Finally, they use a solution will move to tubal egg rushed out to the successful implementation of the collection of the eggs.

Korea scientists used by replication and copy the sheep Dolly, known as the "somatic cell nuclear transfer," method is the first from a dog MOM body made one egg, pumped out its nucleus, then the "father" ear cells nuclei injection into the eggs. New cells and then by chemicals or electrode stimulation split, and then on chemicals has nurtured until planting sufficient cells group, and then move to another dog mother's womb.

Copy only 1.6% success rate

But scientists admit that replication rate remains relatively low. This experiment will 1095 a reorganization of the embryonic implantation 123 receptor (surrogate dog body), only three successful pregnancy. After a gestation period of two months, one of the only surrogate dog abortion, ultimately only 2 surrogate dog can successfully given birth to dog baby. Another copy of the birth of the dog named NT-2, 22 days after the birth of pneumonia mortality, reason unknown. According to the analysis, the success rate for the end of the clone 1.6%.

Some scientists doubt replication technology may damage the genetic code, or failed to complete gene transfer the manufacturing problem of proteins. Copy the animals life generally short, easy infection diseases, together with humanitarian considerations, many scientists urged to stop replication to animals.

There are many human dog "defects"

As always, each clone technology breakthrough in the scientific community and the public in the hotly contested.

Korea scientists in recent years in cloning technology has made breakthroughs. In February last year, Hwang Woo-Suk's leadership team successfully cloned human embryos and embryonic stem cells extracted, first demonstrated human therapeutic cloning, cloning technology to the medical treatment of a historic step. At that time, each extraction of a group of stem cells consume 242 egg cell.

In May this year, Korea scientists clone technology has reached a new height. They successfully cloned human embryos have reached the age of 31, and extract the 11 group stem cells, the total number of egg cell, the success rate for 185 is 16 times before, it can progress rapidly.

Today, the "clone dog" success not only enlarged again had very large "family" of cloned animals, but also for the treatment of human disease brought new gospel. Dogs and humans have some similar physical structure, and like cancer, diabetes and other diseases are dogs and humans common "defects". Therefore, if you have a dog in the early embryonic stem cells can be extracted successfully, and the "safe, effective," for treatment of these diseases, but also help to prove that medical feasibility of human cloning.

However, the "birth of a cloned dog," also raised a number of animal conservationists worry that they thought some people might use cloning technology, engaging in illegal pet trade.

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