Molecular channel in the normal cell growth and Division plays an important role in the process. If an exception occurs in molecular channel change, it can cause a normal cells into cancerous cells.
Duke University's research team found that in patients with advanced non-small cell lung cancer and certain forms of cancer molecular channel causes the more serious, the survival of patients with to much shorter, and some changes in forms of molecular channel is on targeting drug response, you can make them play better therapeutic drugs.
The researchers selected the 69 recurrent non-small cell lung cancer patients and 49 non-small cell lung cancer patients, and they and other 91 early non-small cell lung cancer patients. Researchers on tumor samples gene activity analysis indicates that early-stage non-small cell lung cancer tumor abnormal change in the molecular channel less, while the control group patients tumor "problems" channel relatively more.
Research group leader Portis pointed out that the find and advanced lung cancer related molecular channel and find easy to influence drug molecules form, will be on channel future increase lung cancer cure rate.
Lung cancer is divided into small cell lung cancer and non-small cell lung cancer. Statistics, United States of lung cancer cases, approximately 15 per cent are small-cell lung cancer.
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