World Science report () at the University scientists recently discovered that inhibits a called "Aurora kinase B" substances can kill cancer cells. This discovery will open up new development of anti-cancer drugs.
Aurora kinase protein kinase is a class, you can "amendment" to the levels of protein in the cell mitosis and carcinogenesis. Aurora kinase hyperactivity causes cells not subject to abnormal proliferation, is considered one of the causes of cancer cells.
Many pharmaceutical companies are looking for around Aurora kinase new treatments for cancer, but because of the Aurora kinase is divided into A, B, C, etc., several specific programmes, which are more promising, it was also there. The research group, University of Manchester say that their new discoveries show that Aurora kinase B is a very valuable research objects.
Researchers had hoped that chemical substances inhibit the Aurora kinase A to control cancer found on Aurora kinase B can be more effective in killing cancer cells. Preliminary testing shows that the targeting Aurora kinase B drugs did not cause serious side effects, toxic anticancer drugs are relatively low.
The papers published in academic journals, the journal of cell science. Responsible for the study of Stephen · Taylor said that while suppressing the Aurora kinase A as a potential therapy is still a certain value, but to the Aurora kinase B-focused research more attractive. Researchers intend to and related to pharmaceutical companies to cooperate on this topic.
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