Scientists in human blood found AIDS nemesis

Human blood found AIDS nemesis

[] Message: recently, scientists study found that there is in human blood, a natural ingredient, has the effect of anti-HIV, as long as the blood of a protein structure slightly adjusted, its ability to improve HIV resistant to two orders of magnitude, man can overcome AIDS.

Recent medical research has found that there is in human blood, a natural ingredient has the function of anti-HIV, this outcome is the development of new anti-HIV drugs brought hope. This molecular mechanism and now generic antiretroviral therapy with completely different RNA, but also for those with drug-resistant HIV variants have the effect, therefore to conquer AIDS opened a new front. Researchers also found that, as long as on their chemical structures for small change can drastically improve its antivirus capabilities. The research results at deguowuermudaxue in the latest issue of the journal cell.

The World Health Organization estimates that worldwide there are nearly 40 million people are HIV carriers or living with HIV. Only in 2006, there are 400 million people infected, 300 000 people died because of AIDS. Art RNA drug is by far the most important AIDS therapy, have saved many lives. But HIV has the amazing ability of self improvement, it can continue to produce new varieties with resistance to viruses, so there was concern that many now use major anti-HIV drugs will gradually lose efficacy. In front of the scientists is to find new therapies in place of this drug.

Many people long ago that some elements in the blood on the inhibition of HIV has, but it's not clear which elements of remarkable effect. Ulm University researchers with the most advanced technology for more than 100 million blood protein of anti-HIV effect. They found a they called "virus inhibitory peptides" molecular protein, it has certain fragment relative plenty of anti-HIV effect, and as long as the amino acid composition for adjustment to its ability to improve HIV resistant to two orders of magnitude.

Researchers for this protein for a large number of tests. A testing indicates that some of its derivatives in the blood plasma is extremely stable and, in high concentration of State remains non-toxic to the human body. Another test is to use a synthetic virus inhibitory peptides found it also has a significant effect on HIV, this proves is that in effect, to the exclusion of the anti-HIV is another unknown role of blood elements.

Virus inhibitory peptides mechanism of action is to attack HIV needs a sugar molecule, seizing its nutrients so that it cannot infect the host cell. Therefore it can treat all HIV variants have a dampening effect, but not like art RNA drug that directly attacks kill the virus itself, thus constantly stimulate A new HIV with resistant varieties.

Roger pebereau, United Kingdom Terence Higgins Trust Fund a medical adviser, in the comments of this study, said that it also just in the early stages, but on human research new anti-HIV drugs is of great significance.

"Over time, a growing number of HIV carriers current therapy with drug-resistant and therefore we must pass through the tireless efforts to bring opportunities to patients. This research may take many years, but we hope for the future provision of effective new treatment for AIDS. ”