Men's and women's infertility or stems from gene mutation

[] Message: reproductive biology of a puzzle has been solved, a gene mutation called SUN1, will make the chromosome pairing and genetic recombination, resulted in the generation of mature sperm and eggs. Fudan University, Institute of biology of a recent study, the study of the mechanism of human infertility and medical diagnosis provides new leads.

One of the research group leader, Associate Professor-Xu said yesterday, infertility affects global 10% to 15% of couples, germ cell formation exception is an important cause of infertility. Germ cell formation, the existence of a special form of cell division — meiosis, to make the exchange of genetic material completion of restructuring. What is the "who" to start the transfer of genetic information in half and genetic recombination? over the past hundred years on, the question plaguing the world scientists in the field of developmental biology.

Fudan University Institute of developmental biology of Han Min, Xu, led by research group, found that a man named "SUN1" protein plays an important role. If SUN1 gene mutation that causes the chromosome pairing and genetic recombination, and thus cannot produce the maturation of sperm and eggs.

According to reports, ultraviolet radiation, industrial pollution, agricultural pollution is likely to lead to mutations, ultimately SUN1 cannot produce the maturation of sperm and eggs.