Tuesday, December 21, 2010

Embryonic stem cell injection cannot keep its potential risks in the future

Recently, media, Russia multi-millionaires are their investment from luxurious luxury yachts and jewelry to a stem cell beauty. This isn't a normal stem cells, but from an abortion baby extract stem cells, and then injected into their body, hopes its youthfulness.

Reports that Russia, 58-year-old billionaire Vladimir • Hebron Zaitsev said that he had with wrinkles of the face, has become like the baby-like smooth, even when the children leave scars are gone. Although this kind of anti-aging therapy to spend, but he has become a true believer in treatment. The report also said that fetal stem cells therapy not only eliminates wrinkles and can reduce body fat and loose skin treatment.

Injection of embryonic stem cells really like rich people are so compelling efficacy? really can bring people into a child?

Cell transplantation to matching

"This kind of behavior is very unscientific and extremely dangerous thing. "Chinese 863 plan" organs "significant special overall team leader, transfusion medicine Academy of military medical sciences, Director of the Pei xuetao Professor holding strongly negative attitudes.

Bai Xue Tao said that people can't easily do cell transplantation. Every cell has a different development model, in medicine called individual immune barrier, this barrier prevents the individual cells of the transplantations at will. Transfusion to matching, bone marrow transplantation have to undergo strict typing,. Moreover, even if matching is successful, the treatment of cancer and leukemia for bone marrow transplantation, but also to be migrated to the use of immunosuppressive drugs and chemicals, the purpose is to destroy the immune system, otherwise the immune system can automatically identify, exclusion of foreign cells. Like some liver, kidney transplant to lifelong taking immunosuppressive agent, inhibiting the immune function of recovery, because once the recovery, rejection is inevitable.

Pei xuetao said, direct injection, fetal stem cells without typing, the recipient's immune system can be identified, easily lead to rejection. As to the matching, he said no kinship with matching success probabilities about 100 to 2 STS, in theory, in a large number of fetuses, find matching almost negligible. From ethics, aborted fetuses into the sale of goods, is not allowed. Therefore, from biology and medicine and ethics, this is not feasible.

Potential risks in the future

Since immune barrier prevents cell transplantation, why injection fetal stem cells would seem young?, Bai Xue Tao said that early embryonic cells is childish and primitive cells, immunogenicity also less obvious, since the existence of multiple cytokines, eyes for a brief period of time may feel young, but after some time, along with the stem cell development and function of cells mature, allogeneic cells of immunogenicity can be demonstrated that the future of the great risk.

Pei xuetao said, direct injection of fetal stem cells exist in three types of risk. First, the stem cells inside the body is to be further developed, wait for it to mature, the surface antigens of gradually revealed. Because of the incoming cell vitality vigorous, with comparison of immune system or bone marrow maturation, which attacks the skin, liver, kidneys, causing damage to tissues and organs. Second, the early fetal stem cells in the external environment is likely to occur under the influence of cancer, malignant transformation of cells. The third is directly to the cells for transplantation, there is also a biosafety, the potential risk of HIV infection, AIDS and many other viruses are spread by a mother to the baby's vertically, which may be transmitted to recipients. Therefore, from a technical perspective, safety of such behaviour is extremely dangerous.

Stem cells do not have access to a mature application period

Stem cells and regenerative medicine is an emerging discipline, the world is investing substantial funds and organizations many scientists conduct research. Pei xuetao said that now is the peak period of the study, the application will take some time on a large scale. At present, the clinical application of stem cells is the most mature treatment of blood diseases of bone marrow transplants, cord blood transplantation. In Europe, started using stem cell transplantation in the treatment of myocardial infarction and vascular diseases, stem cell treatment itself can cause malignant transformation of cells in research. As for the embryonic stem cells (i.e. therapeutic cloning) across the world have no access to any application, to be safe and effective, and controlled, have a long way to go.

At the national level, some small hospitals and even a beauty salon that he can do stem cell aging treatment, advocacy sagacity. To this end, the Pei xuetao remind people not to listen to these misleading and speculation, don't take their own lives to joke, when experimental products. In recent years the rapid progress of stem cell research, but there is not a mature technology. Now, only a small part of the access to clinical application, a significant part is still in the research, how to evaluate the effectiveness of stem cells, security, control of side effects, reduce risk, but also for long-term scientific research and demonstration. He would advise those who want to pass the anti-aging medical technology should take the sensible and careful attitude of waiting for stem cell technology matures, the so-called live forever, at least there is youth.

No comments:

Post a Comment