Tuesday, December 14, 2010

Bone marrow stem cells can be treated with male infertility.

<P> U.S. researchers used bone marrow stem cell therapy for male infertility investigation revealed the effectiveness of this treatment is very promising. .Researchers in the March issue of American Journal of Pathology, published a paper entitled "Transplantation of bone marrow stem cells into the testes results of" research report. .</ P> <P> researchers said that when the case of infertile couples, the husband and wife are likely to be caused by cause of infertility. .Male infertility may be the proliferation and differentiation of germ cells or not supporting cells (supportingcells) caused by the dysfunction. .New research is the key to using stem cells to replace lost function in germ cells or supporting cells. .</ P> <P> University of California at Los Angeles Medical Center, Dr. Ronald De Luofu • Swift team led by chemical or genetic methods for generating non-fertility of the mice were studied. .Test, they will carry the green fluorescent protein bone marrow stem cells into the testes of mice, using fluorescent protein tracing traces of action of bone marrow stem cells. .It was found that research carried out in 12 weeks time, the injected bone marrow stem cells not only have to stay and survive in the testes, and showing the germ cells or supporting cells of the special form, indicating that the differentiation of stem cells appeared. .In addition, researchers around the mice's own cells are also found in the same band fluorescent cells divided to prove where the cell environment may affect the development of the injected stem cells. .</ P> <P> To further determine the injected bone marrow stem cell differentiation status, the researchers examined the cell surface expression of specific proteins. .The results showed that both the germ cells or supporting cells expressed the differentiated cells can only be found in the marker protein. .</ P> <P> Overall, the study data show that bone marrow stem cells have the potential to differentiate into sperm production associated with testicular cells (germ cells and supporting cells) capability. .However, the researchers say, is interesting and not fully differentiated germ cells into sperm, suggesting also need other factors or cell signaling. .Who can help the sperm produced by other factors (such as hormones) will be their focus of future research. .In addition, the trials used bone marrow cells are a mixture of a variety of stem cells, the researchers confirm what the next step will really be able to occupy the testicular cells and the differentiation. .These in-depth study will be the use of bone marrow stem cells for future treatment of human male infertility, the key to success. .</ P> </ p>.

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