And doping dependence of related genes be cracked

[] Message: Japan researchers in lab mice found associated with doping dependence of a gene, it might help people development for this class of drugs.

According to the Japan Asahi Shimbun website reported that Japan Nagoya City University researchers to design an animal experiment. They produced a special feeding bins, boxes of red light, experimental rat nasal tip gently touch the light below

Of small holes, you can get a small amount of stimulants. Researchers also fostered an experimental rat, its guiding synthesis neurotrophic factor "GDNF gene" does not play a role. This experimental laboratory mice and rats are normally placed in specially constructed box feeding, the researchers will compare two rodent dependence on stimulants in the required time.

Experimental results show that the average normal mice 20 days with stimulants, and such dependency gene exception group mice average 15 days of suffering from this disease. Since then, the researchers are no longer available to the feeding tank performance-enhancing drugs. Three months later, when the researchers again to open the feed in the red traffic light, direction "synthesis" GDNF gene does not play a role in experimental rats will use hard nose touch light below the small holes, faster than the control group experimental mouse double. This indicates that, if the experiment mice synthesis "GDNF gene" factor is not working properly, they are more susceptible to doping dependence of recurrence, and easier.

At the same time, the researchers use amino acid molecules for the treatment of these experimental rat stimulant dependence syndrome, amino acids can increase "GDNF" neurotrophic factor. They give experimental murine disease for 5 days, the injection of amino acid supply interruption of stimulants. 5 days later, these experimental rodents to stimulants in significantly lower. Researchers believe that the "GDNF" factor of the increase in the number of experimental rat's ability to resist the temptation of stimulants.

Researchers say they are still not clear whether this finding applies to people, but has been the outcome of research and development for the treatment of stimulant dependence of drugs provide clues.