Our major animal diseases vaccines and diagnostic techniques to obtain a series of new breakthroughs. Today, the Ministry of agriculture official in Beijing announced that the national avian influenza reference laboratory has developed three novel avian influenza vaccine and a avian influenza diagnostic technology. 3 new vaccine combined use, complementing each other.
3 new vaccines are "avian flu (H5N1) vaccine," "codon optimization the H5 subtype of avian influenza HA gene DNA vaccines" and "avian influenza" recombinant subunit vaccines. Where the country in the world's first "avian flu (H5N1) vaccine" that serological methods to distinguish between the "natural infection" and "vaccine immune reaction", therefore appear to be highly effective, safe. "The H5 subtype of avian influenza for rapid diagnosis of UPT", just 10 minutes can be quickly detected the H5 subtype of avian influenza virus.
The official said, the prevention and control of FMD in China to do the work, the national science and technology reserves of foot and mouth disease reference Labs has also successfully completed the "foot-and trivalent inactivated vaccine" laboratory research. The tests confirmed that good safety and efficacy. Compared with traditional vaccines, vaccine using a virus strain characteristic fine. Immunogenicity, Antigen spectrum range, on experimental animals and vaccine material has a good adaptability. The second is more efficient. A vaccination can prevent three serotypes of foot and mouth disease virus attacks. The third is to reduce the stress response. Application of trivalent vaccine prevents multiple injections to reduce repeated injection-induced stress.
In major animal diseases diagnosis technology in a number of new breakthroughs that the national avian influenza reference laboratory successful production of the enzyme-linked immunosorbent assay (ELISA) diagnostic kit, Hi test diagnostic kit, H5, H9 subtype specific PCR for rapid diagnosis kits and H5, H9 subtype specific antigen-capture ELISA diagnostic kit, etc.
National reference laboratory for foot and mouth disease has successfully developed the foot shaped PCR diagnostic kit, indirect hemagglutination test diagnostic kits and liquid blocking ELISA diagnostic kits, etc., in surveillance and diagnosis of the work has been widely used.
The successful development of Nanjing Agricultural University of Streptococcus suis 2-pathogenic strains of triple PCR detection kits promptly applied to disease monitoring and diagnosis, disease prevention and control has won.
Allegedly, the successful development of our earliest bird flu vaccine (H5N2 subtypes) outbreak in early 2004, the highly pathogenic avian influenza during the first mandatory immunization using mainly vaccines, has used the H5 subtype of avian influenza prevention and control. On the basis of this vaccine, the national avian influenza reference laboratory applications reverse genetics techniques and recombinant DNA technology has been successfully "reorganization of the avian influenza virus vaccine" (H5N1 subtype), "the avian influenza virus vector recombination chicken pox vaccine" and "avian flu-ND recombinant live vaccine" 3 new bird flu vaccine.
Experts say that the "reorganization of the avian influenza virus vaccine" (subtype H5N1) is currently the most advanced, the technical content of the highest influenza vaccines, can solve water birds immune and waterfowl poison challenges. The vaccine in China and Viet Nam, and other countries have mass, practice shows that the immune to good effect.
"Avian influenza recombinant fowlpox virus vector vaccine" conducive to the identification of immune and wild virus infection, immunity protection integrated assessment than similar technology products. "Avian influenza, Newcastle disease recombinant live vaccine" is the first safe and effective negative-strand RNA virus live vector vaccine, represents the future of animal and human vaccine research and development an important direction of development. The vaccine has China's intellectual property, compared with the traditional vaccines, vaccine efficiency high, the immunity effect ideal, high security, low production costs, save time, increase the quality of poultry meat.
Currently, several new major animal diseases vaccines and diagnostic reagents have been successfully developed and has been promoting the use of large, international and domestic has aroused strong repercussions. United States, Europe, and so many research institutions given extensive attention. The World Health Organization (WHO), World Organization for animal health (OIE), the UN food and Agriculture Organization (FAO) and other relevant international organizations and to accept our vaccine assistance, on the avian influenza in China, at the global and regional role and level of scientific research of China's vaccine given high marks.
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