Mixed anticancer agent is expected to treat AIDS

University of Minnesota Medical Center scientists say they found that the United States food and Drug Administration approved, currently used for the treatment of cancer and cancer of the two drugs Cytidine (decitabine) and Mr Peter (gemcitabine), expected to be effective in the treatment of AIDS. In experimental animal models of rats, mixed drugs can cause AIDS virus mutate and death, scientists refer to it as "lethal variation".

New discovery on AIDS research of epoch-making significance, because this is people looking for the first time to a non-toxic side effects against the AIDS virus. Scientists believe that as a result of Cytidine and kin-Peter are two allowed use of drugs, and if their research results in large animal model is also effective, then will be relatively easy to accelerate the development of a suitable for human drugs.

Study participants included molecular Virus Research Institute and dental school of molecular virologist Dr. Louis · zamansky and Christina Aguilera · Dr Crowther, and drug design center drug chemist Dr. Steven · Patterson. Zamansky, said their findings to ultimately helping global 3300 000 HIV carrier unlock disease brought hope. Related articles published in the recent "Virology" Magazine Web site.

AIDS virus in human variation and change rapidly. Now commonly used drugs in the main role is to inhibit growth and replication of the virus, Cytidine and kin-Peter new drug composed of vice-versa, it forced the virus mutate runaway and disaster. Zamansky, AIDS virus mutation ability makes it difficult to capture and deal with it, "we use a virus that behavior, through the promotion of virus mutation rate, so that the virus itself as a weapon to attack their own".

Scientists found that they used to kill HIV medications for concentration on cell toxicity cannot be detected, at the same time, to effectively kill laboratory culture of HIV drug concentrations well below the people use both of these drugs to treat cancer, drug concentration. Existing approved drugs have been used to develop treatment other disease, in the medical sector is considered a low-cost and fast way to get a new drug, called drug repositioning (drug repositioning).

It is learnt that Cytidine and kin-Ze has been conducting experiments of the early stage clinical trials, the drug may be found to confirm, as HIV effective antiviral treatment. Currently, scientists are adjusted so that the composition of drugs can be absorbed by the anti-HIV drug taken orally.