Technology channels () message: United States New York Downstate Medical Center scientists discovered that the brain preserve memories of the molecular mechanisms and to prove, by inhibiting protein kinase Mzeta, you can erase the contents in the computer hard disk, wipe the long-term memory. The discovery will be used for the treatment of chronic pain and amnesia.
Although scientists as early as 30 years ago discovered hippocampus in neuronal synaptic connections between continued strong phenomenon, and the strengthening of ties in the formation of memory and storage memory plays an important role. But has not found any evidence. Long-term potentiation (LTP) response is considered a brain basis for learning and memory, scientists assume that it is divided into perception and maintain two stages. To test this hypothesis, they need to live in LTP maintenance phase reversal, check the long memory of the information is lost. Scientists study found that in fact is a protein kinase Mzeta through continuous strengthening of synaptic connections between neurons to save long-term memory. Test in mice, researchers in the kinase inhibitor injection into the rat hippocampus, results reversing the process, scientists LTP maintain "wipe" the mouse 1 day ago, or even a month ago memories. The memory storage feature only corresponds to the protein kinase inhibitors of the molecule Mzeta, does not interfere with memory, that is, the erasure of long-term memory in the brain does not affect the result in a new memory.
The discovery will help in a variety of treatment of diseases of neural connections, such as neuropathic pain, phantom limb syndrome, Dystonia, PTSD, etc. Earlier this year, the Medical Center scientists reported protein kinases and Alzheimer's disease-related Mzeta, it might hinder the memory functions.
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