Why some people do eat no fat, but some people drinking water is President of meat? from the Washington University in St. Louis, United States of microbiologists Jeffrey · Gordon and Frederick · backheden pointed out that the human body compared to the number of bacteria in food may be the cause for the obesity of a more important factor. They think that life in human intestinal bacteria, composed of different might be able to explain why some people are particularly vulnerable to fat while others stay slim.
Bacterial stocks of door opened fat
Gordon and backheden two-person point of view based on a study. In the experiment, the mice are divided into two groups, a group of bacteria living in normal conditions, while the other is placed in a sterile environment. Aseptic conditions and the growth of mice fat than normal growth of mice under conditions of low 42 per cent, but their food in calories than normal mice food calories up to one-third of the content. When sterile mice at doses from ordinary mice of bacteria, their body fat in just two weeks has increased by 57 per cent.
"In our intestinal parasitic bacteria within the group, particular categories of missing may exist or for those of us from food harvest and storage of energy in the process there is a big impact. "Gordon jump road. However, kill these bacteria of the digestive system is not a viable option, because obviously the effect of weight loss is far from appearing before it can cause a variety of deadly opportunistic infections.
The team found: normal conditions, the intestinal bacteria use a double cross strategy, first to decomposition in General cannot be digested food ingredients, effectively increasing the body's ability to obtain the number of calories; after some bacteria can produce through inhibition of intestinal called "throw fasting fat cell factor" (fasting-induced adipocyte factor, Fiaf) enzymes to enhance fat storage. Fiaf's role is to let the body fat into the fat cells of the "gate".
"Fiaf is a digestive organs within the direct control of bacteria — and this discovery is very exciting. It enhances a possibility: an obese or slim tendencies may be part of life in the intestinal microbial communities in composition. "Dr. Gordon said.
Traditional treatment of obesity requires long-term control diet and therefore often fail. Gordon believes that this study shows the Fiaf derivatives will have the potential to become effective in the treatment of drug.
"We passed on the cultivation of aseptic conditions in mice know the importance of the Fiaf. This so-called aseptic mice than normal mice eat much, but fat is less than the normal mice. "Backheden said. In aseptic mice, no inhibition of intestinal lining cells of bacteria in the Fiaf, resulting in more distant Fiaf to limit the fat cells in fat storage.
Changes in bacterial composition for healthier
"Fiaf is we found many of the affected intestinal parasitic bacteria many one of the main factors. "Gordon said," in adults who live in the intestinal 10 trillion to 100 trillion bacteria, this huge microbial populations through evolutionary produced some through the manipulation of our body's biology so that their own and we benefit from the human body. ”
In fact, Gordon more willing to intestinal microorganisms as a body organ that can precisely according to the needs of our physiology. "After millions years together with humanity, microbial CoEvolution has learned how to control the human gene network. By defining these networks, we are able to learn new ways to improve health. ”
Along the way, maybe one day, doctors will be able to for a digestive organs in the composition of microorganisms for specific changes to improve human health, or they will be able to put the intestinal microbial natural products as a manufacture.
"As the research progressed, we for gene mapping horizons become more extensive. A new understanding is the number of the cells, each of us is made up of 90% of bacteria and 10 per cent of human cells. Intestinal microbial genomes may contain a number of genes is our human gene of 100 times. These genes provide us with some further development of the human body does not have to own. "Gordon says.
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